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What Is THC-O?

You may have heard of Delta-8 THC and Delta-10 THC. Recently, a new cannabinoid called THC-O has entered the market. THC-O is a synthetically-produced cannabinoid that does not exist naturally in Hemp. Through chemical research and experimentation, some manufacturers discovered that Delta-8 THC, which is produced from manipulating CBD in a lab, can be chemically processed to produce THC-O.

THC-O is marketed as a pain relief option. However, there is very little research on THC-O. Anecdotal evidence suggests that it is potent, hallucinogenic, and potentially dangerous. THC-O manufacturers are less regulated than CBD producers, which means their products can be laced with chemicals and solvents.

As for the effect of THC-O on the body, it seems to be harsh and forceful as opposed to CBD’s gentle cooperation with the endocannabinoid system.

What Is THC-O?

THC-O is a synthetic cannabinoid that is produced from CBD. It is not found naturally in Hemp, therefore no CBD product contains THC-O.

CBD is initially processed to make Delta-8 THC. Then, manufacturers add acetic anhydride to the Delta-8 THC to turn it into THC-O.

Acetic anhydride is a corrosive and highly flammable chemical that is used to produce plastics, perfumes, cosmetics, and cleaning products

What Does THC-O Do to the Body and Mind?

It is thought that THC-O is highly potent and psychedelic. Like many cannabinoids, its effects are milder in small doses. In larger quantities, THC-O is hallucinogenic and produces a strong sedative effect.

By some calculations, THC-O is three times more potent than THC—the psychotropic cannabinoid responsible for the sense of ‘high’ associated with marijuana.

How Long Does It Take To Absorb THC-O?

THC-O hits its peak about an hour after it’s consumed. Once it is metabolized by the liver, it delivers all its psychoactive punch in a strong wave-like effect.

Is THC-O Dangerous?

Due to the product’s novelty, there is no scientific or medical research on the effects and side effects of THC-O. This makes it an unknown cannabinoid compound without any proven safety protocols.

THC has been associated with psychotic episodes and the triggering of schizophrenia, particularly in youngsters. It may also lead to high blood pressure and heart problems. It is possible that THC-O may have a similar effect.

There are many additional reasons why THC-O may be considered dangerous.

THC-O Manufacturing Practices

THC-O manufacturers are producing THC-O under murky conditions and in labs of questionable quality. There is no Certificate of Analysis showing the potency of THC-O or the presence (or absence) of chemicals and residual compounds in the final product. The actual production process may leave behind solvents and other unwanted chemicals.

The CBD market is largely unregulated. Compared to the THC-O market, however, CBD producers and manufacturers are the epitomai of rules, regulations, and quality control.

Synchronicity carries several tests throughout our production process. You can check the Certificate of Analysis online for any of our products by simply entering the Lot Number.

THC-O Effectiveness

There is no research confirming that THC-O can offer therapeutic pain-relieving qualities. Also, there is also no research regarding the potential for addiction to THC-O.

Conversely, CBD has been thoroughly researched. The World Health Organization has concluded that:

“CBD exhibits no effects indicative of any abuse or dependence potential…

There is also preliminary evidence that CBD may be a useful treatment for a number of other medical conditions…

CBD is generally well tolerated with a good safety profile. Reported adverse effects may be as a result of drug-drug interactions between

CBD and patients’ existing medications…

To date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD.”

What Is the Difference Between CBD And THC-O?

CBD and Full-Spectrum Hemp Oil are botanical products whereas THC-O is as far from natural Hemp as possible. However, there are many other differences between CBD and THC-O as well.

CBD vs. THC-O: Gentle Nudge vs. Violent Effect

The way CBD works is by gently nudging our endocannabinoid system to work better and more effectively with its endocannabinoids. CBD has minimal direct interaction with the CB1 and CB2 receptors. Also, many Full-Spectrum Hemp Oil consumers choose to microdose—i.e. take small doses of CBD throughout the day to make full effect of CBD.

On the other hand, THC-O seems to have a violent and immediate effect on the body. The psychedelic, sedative, and hallucinogenic effects are felt within an hour and dissipate equally fast. The body has no time to adjust to the onslaught or absorb any benefits.

CBD vs. THC-O: Botanical vs. Synthetic

A crucial difference between CBD and THC-O is that CBD is a botanical cannabinoid found in Hemp.

The process to produce CBD is completely mild compared to THC-O.

In the case of THC-O, acetic anhydride has wiped out all the terpenes and flavonoids, leaving behind a lab-produced, tasteless, and odorless thick brown liquid.

CBD vs. THC-O: Well-Researched vs. Unproven


There is no such evidence for THC-O, which remains an unknown, untested artificial product.

CBD vs. THC-O: The Entourage Effect

In his landmark 2011 paper, “Taming THC,” Dr. Ethan Russo described how the whole is greater than the sum of its parts when it comes to Hemp. Hemp’s hundreds of cannabinoids, terpenes, and flavonoids work synergistically to enhance each other’s effects.

Instead of focusing on any single compound, our Full-Spectrum Hemp Oil contains over a hundred cannabinoids.

Since THC-O is an artificially produced cannabinoid, it lacks any entourage effect.

Is THC-O Legal?

The legality of THC-O is an open question.

The 2018 Farm Bill declares that cannabinoids produced from Industrial Hemp are legal if they are produced from Hemp that has less than 0.3% THC in dry weight.

THC-O is a byproduct of Delta-8, which is a byproduct of CBD, which is a naturally occurring Hemp cannabinoid. Does that make THC-O legal?

Additionally, there is another legal matter that questions the legality of THC-O. The 1986 Federal Analog Act states that chemicals that are “substantially similar” to a controlled substance should be classified as Schedule 1 substances.

Under federal law, THC is a Schedule 1 substance. Since THC-O’s effects are similar if not more pronounced to THC, this Act would make THC-O illegal.

Therefore, there seems to be a legal limbo regarding the legality of THC-O. It is sold across the United States but countries like the United Kingdom do not allow the sale of THC-O. Interestingly, the UK forbids even Delta-8 THC, which is milder than THC-O.

Why Would You Consume A Chemical Compound Of Unproven Effect?

Why should we interfere with nature when it has already given us a botanical compound with so many benefits?

This is a question our team at Synchronicity often asks. We want our Full-Spectrum Hemp Oil to be as close as possible to how nature intended. That’s why we intervene as little as possible. Our Hemp plants are our most precious asset, containing all of Hemp’s botanical wealth.

Instead of tinkering with nature, we have partnered with her. This way, our Full-Spectrum Hemp Oil products are teeming with Hemp’s holistic anti-inflammatory, antioxidant, and mood-supporting qualities to help you lead a happier, healthier life.


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ContentsWhat Is THC-O?What Does THC-O Do to the Body and Mind?How Long Does It Take To Absorb THC-O?Is THC-O Dangerous?THC-O Manufacturing PracticesTHC-O EffectivenessWhat Is the Difference Between CBD

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