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With over a hundred cannabinoids identified so far, Hemp still holds a lot of healing potential.
CBD and THC have attracted the most attention as they are the most prominent cannabinoids found in Hemp. However, researchers have started to investigate the rest of the cannabinoids as well. The goal is to see whether their therapeutic properties can improve our lives and help alleviate conditions as diverse as inflammation, auto-immune disorders, glaucoma, and mood disorders, among others.
One of these cannabinoids under research is CBG, or cannabigerol. It is found in minute quantities in Hemp, hence its high price. CBG was only discovered in 1964 and is slowly getting the attention it deserves as it is displaying promising results in terms of anti-inflammation, neuro-protection, and anti-bacterial treatment.
CBG is legal in the United States as long as it is produced from Industrial Hemp. It is also non-intoxicating and non-addictive.
What You Need To Know About CBG
Where Does CBG Come from?
All cannabinoids in Hemp are produced from CBGA; an acid that is the precursor of all cannabinoids. Once CBGA is born, it slowly produces THCA, CBDA, and CBCA. These are the acidic forms of the cannabinoids we know.
As air and sunlight oxidize the plant, a process called decarboxylation takes place and the cannabinoids lose their acidic compound. Hence, THCA becomes THC, CBDA turns to CBD, and CBCA develops into CBC.
What traces of CBGA are not turned into any of the other three main cannabinoids convert to CBG. This is why Hemp contains up to 20% of CBD but less than 1% of CBG.
How Does CBG Work?
Our body is equipped with an endocannabinoid system (ECS). The ECS produces two cannabinoids, anandamide and 2-AG. These bind with two receptors, CB1 and CB2.
When there is something amiss in our body, our endocannabinoid system sends anandamide and 2-AG to bind with the CB1 and CB2 receptors and inform our body to fix the problem.
CBD appears to interact indirectly with these two receptors, telling our body to use more efficiently its own cannabinoids.
Unlike CBD, CBG appears to interact directly with the CB1 and CB2 receptors of the endocannabinoid system. By binding directly to the CB1 and CB2 receptors, CBG may be more efficient and powerful at healing and alleviating certain ailments and conditions.
CBG also seems to interact with other brain receptors apart from CB1 and CB2. Research suggests it affects the 5-HT1A receptor, which is a serotonin receptor responsible for mood, appetite, anxiety, aggression, memory, and sleep.
Finally, CBG also binds with the capsaicin receptor TRPV1, which is responsible for pain and heat perception and is implicated in inflammation, cancer, and immunity.
What Is CBG Oil Used for?
Due to its scarcity, CBG had not attracted much attention until recently. However, initial trials and preliminary findings are proving promising.
CBG for Glaucoma
Research suggests that CBG may lower eye pressure and thus help with glaucoma. When fluid increases in the front part of the eye, it puts pressure on the eye itself and ultimately destroys the optical nerve. CBG appears to lower eye pressure and may, therefore, protect from glaucoma.
CBG for Inflammation
Like most of the other cannabinoids, CBG displays anti-inflammatory qualities. Initial findings suggest that CBG may help with conditions related to inflammation such as irritable bowel disease and colitis.
CBG for Neuroprotection
As people live longer lives, they also suffer from nerve degeneration. Alzheimer’s, Parkinson’s, and multiple sclerosis are all neurodegenerative diseases, where the central nervous system and the peripheral nervous system nerves get damaged or destroyed. They then fail to transmit messages to the body or send the wrong ones.
CBG displayed promising results when administered to people with Parkinson’s disease. Further studies are underway to study its potential for that and other similar diseases. As there is still no cure for such conditions, finding one would greatly improve the quality of life and life expectancy of millions of people.
CBD for Pain Management
The fact that CBG binds with the TRPV1 receptor suggests it may help alleviate acute or chronic pain. Current pain management medication is often addictive or has potentially severe side effects, so this possible application is particularly exciting.
CBG for Infections
CBG also appears to have anti-microbial qualities. Research suggests that CBG may be a potent antimicrobial agent to treat antibiotic-resistant MRSA infections—a subject of increasing worry to doctors worldwide.
Additionally, topical creams with CBD and CBG have shown to improve skin infections.
CBG for Bladder Dysfunction
In studies, CBG seemed to reduce bladder contractions. This makes it potentially useful in treating bladder dysfunction.
CBG for Appetite Loss
Stimulating appetite can be crucial for people with cancer or HIV; diseases that often lead to appetite loss. CBG could be a helpful tool for people suffering from poor appetite.
CBG for Anxiety
CBG’s potential ability to directly bind with brain receptors without being psychotropic makes it a possible candidate for alleviating anxiety. It could be particularly beneficial for relaxing tense muscles and bringing a sense of peace to people.
As with pain management, current anxiety medication has potentially severe side effects. A new medicine that’s not addictive and has far fewer and milder side effects would help millions of people worldwide.
CBG Mediates THC
Just like CBD, CBG appears to moderate the psychotropic effect of THC. In states where THC sale is legal, taking CBG along with THC might help patients experience fewer psychoactive and hallucinating effects from THC.
Why Is CBG Expensive?
A quick look at cannabinoid products shows that CBG is more expensive than CBD. There are various reasons for this.
First of all, CBG has not yet acquired the attention that CBD has. This means there is less demand for CBG. If CBG is shown to be effective, demand will increase and supply should follow suit.
High Production Cost
Second, a significant reason for CBG’s high price is the cost of production itself. CBG only accounts for 1% of cannabinoids in Hemp compared to 20% for CBD. This means that producers need 20 times more Hemp to produce the same amount of CBG as CBD.
The third reason has to do with the speed at which compounds get oxidized. CBG is only found in small quantities in Hemp because CBGA quickly turns to CBDA, THCA, and CBCA, leaving just traces to develop into CBGA.
As a result, Hemp growers have two choices. They can let their plants mature, extract CBD and other cannabinoids, but end up with very little CBG.
Alternatively, they can harvest their Hemp plants earlier—approximately two weeks earlier—so that they can get as much CBG as possible. However, in this case, they are sacrificing the production of CBD and other cannabinoids for the sake of CBG.
Expensive Extraction Process
The last reason for CBG’s relatively high price is that the extraction process is expensive compared to CBD. Given the tiny quantity of CBG in Hemp, laboratories need special equipment to extract the little CBG available.
As more research is directed towards CBG and its potential is better understood, growers are considering whether developing new CBG-rich Hemp strains might be the answer to their problems.
CBG vs CBD
Both CBD and CBG are non-intoxicating cannabinoids that produce similar effects on the body. They are both well tolerated and produce relatively few side effects.
Some of their effects overlap: CBD and CBG are both anti-inflammatory, pain relievers, and have shown potential for treating anxiety and infection.
However, CBD and CBG act differently on the body, as CBG binds directly with the CB1 and CB2 receptors while CBD acts indirectly.
The Entourage Effect
Research suggests that together is better when it comes to cannabinoids. This is the so-called entourage effect. The term refers to the increased potential of cannabinoids when they are taken together. When combined, cannabinoids seem to increase each other’s potential: the end result is more than the sum of each individual cannabinoid’s potential.
Therefore, it may be immaterial to choose CBD or CBG. The best thing is to select a high-quality, American Hemp Oil that contains CBD and CBG along with the other cannabinoids. By taking in all the potential of Hemp, you are fully supporting your body’s wellbeing.
Full-Spectrum vs Broad-Spectrum Hemp Oil
The best way to experience the entourage effect is to take Full-Spectrum or Broad-Spectrum CBD.
At Synchronicity, aFull-Spectrum 500mg CBD Tincture contains all the cannabinoids, flavonoids, and terpenes found in Hemp, including CBD, CBG, CBC, CBN, and traces of THC—under 0.3% for the Hemp Oil to be legal.
Broad-Spectrum CBD Oil is like Full-Spectrum but without the THC. People who are concerned about drug tests at work often opt for Broad-Spectrum CBD.
In both cases, people would be getting CBD and traces of CBG.
CBG Side Effects
CBG could interact with medication such as blood thinners, blood pressure medication, cholesterol medication, and even antibiotics. Before taking CBG, it is best to consult with your doctor as even over-the-counter medication could interact with CBG.
How Do I Choose a CBG Product?
If you are looking to take CBG in larger quantities than those contained in CBD products, you should choose your product carefully.
It’s best to choose products made from Hemp grown by certified American farmers. Hemp is a bioremediation plant, absorbing heavy metals, pollutants, and pesticides from the soil. Many countries, especially in Asia, use Hemp to clean up contaminated soils. You definitely do not want these substances in your body.
Also, find a producer who displays their Certificate of Analysis with clear documentation of all the cannabinoids, flavonoids, terpenes, and carrier oils in their product. This means the product is fully tested and safe to consume. American products are thoroughly tested, unlike some imported ones.
CBG: a New and Promising Cannabinoid
Discovered in 1964, CBG has been studied very little compared to its more famous siblings, CBD and THC.
CBG seems to hold promise as an effective anti-inflammatory, anti-anxiety, and neuroprotective cannabinoid. It’s also a possible future treatment for glaucoma and infections. However, more research is needed before we can use it in a medicinal capacity against specific conditions and ailments. For example, we first need to determine the right dosage and its interaction with other medications.
CBG is expensive because Hemp only contains small amounts of it. However, assuming its potential is confirmed and demand increases, new CBG-high Hemp strains may be developed and prices could decrease.
Now that the world of cannabinoids has opened up, new benefits and applications of Hemp are revealed every day, including CBG!
Here at Synchronicity we avoid harsh CO2 extraction processes, use sustainable farming practices for all of our plants, and oversee the gentle hand-pressing and coconut oil fusion of our products. We work with third-party testing facilities to ensure that everything we create is safe and reliable. Synchronicity—the passionate Hemp Oil producers.