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What Is CBDV?

Hemp is packed with hundreds of cannabinoids, terpenes, and flavonoids. While CBD has been the main focus of scientific attention for decades, many other cannabinoids are only now gaining scrutiny and moving into the spotlight.

CBDV is one such cannabinoid, first discovered in 1969. It has been described as the precursor of CBD, and like CBD, it is non-psychoactive. However, unlike CBD, it took almost 40 years for researchers to look into CBDV’s potential and to unearth its potential, which ranges from anti-nausea to anti-anxiety and anticonvulsant effects.

A significant impediment to further research into CBDV is that it is more plentiful in marijuana than Hemp. Since the cultivation of marijuana is still controlled and highly regulated, producing CBDV can be challenging.

A further obstacle is that it is mostly found in specific strains of cannabis—strains that are fast disappearing.

Where Does CBDV Come from?

CBDV comes from cannabis and is closely related to CBD.

As a cannabinoid, CBDV has a particularity: it is found in what are called landrace Indica strains of cannabis. Landrace strains are the strains that have not been crossbred with other plants of the same species.

Unfortunately, landrace strains are becoming rarer as they are difficult to find and grow. Most cannabis strains have been interbred to generate specific strains according to our needs: several strains are high in CBD content, others are drought-resistant, and some are disease-resistant.

This leaves us with very few landrace strains that have not been crossbred to improve their potential. The most common landrace Indica strains are currently found in Mexico, India, and Pakistan.

Is CBDV Legal in the United States?

CBDV is legal in the United States, as long as it is produced from Hemp rather than marijuana. And this is where the problem lies: Hemp contains very little CBDV. Therefore, processing Hemp for its CBDV content is time-consuming and, ultimately, delivers very little CBDV.

However, obtaining CBDV from marijuana is still illegal at the federal level, since marijuana has not been legalized across all 50 states. Some states have legalized the use of recreational and/or medicinal marijuana, but this is only at a state level. As a result, getting CBDV from marijuana can only happen at the state level.

What Is CBDV’s Potential?

The main areas where CBDV has been researched are nausea, epilepsy, muscular atrophy, motion sickness, and seizures.

Even though research into CBDV started late, preliminary results seem promising.

CBDV as an Anticonvulsant

CBDV has attracted attention as a possible anticonvulsant. People suffering from seizures could benefit greatly from a natural, yet effective compound that could limit or decrease the intensity of their seizures.

Research suggests that CBDV acts differently on the body than CBD. While CBD interacts with the endocannabinoid system and nudges it to work better, CBDV takes a different route. Instead of interacting with the same endocannabinoid receptors as CBD, namely CB1 and CB2, it binds to the TRPV1, TRPV2, and TRPA1 receptors.

These receptors are found in the central and peripheral nervous systems. They are tasked with regulating inflammation, pain reflection, and temperature perception. When these receptors are out of balance, they may send erroneous messages, such as feelings of intense pain.

The TRPV1 receptor is involved in the onset of epilepsy and is particularly active in the hippocampus. Controlling these receptors could regulate epileptic seizures and crises.

CBDV as an Anti-Emetic

A further area of research has focused on how CBDV might improve nausea and motion sickness.

CBDV appears to be an agonist of CB1 receptors—i.e. it binds to CB1 receptors and activates them to produce a biological response. As CB1 can help with nausea, CBDV may have a similar effect. This is confirmed by studies on rats that have shown it to be effective in alleviating nausea symptoms.

Further research is required to understand whether CBDV has the same effect on people and whether it can help people who are debilitated by nausea. People undergoing chemotherapy, for example, would certainly benefit from a botanical compound that could ease their nausea.

CBDV for Other Health Purposes

As more trials get underway, new findings emerge about CBDV’s potential. Some findings suggest that CBDV could be helpful with muscular atrophy. Initial trials on mice and rats showed that CBDV could help with inflammation and muscle function. Of course, human trials are required to support these findings.

Another area of interest is how CBDV could help with brain function and neurological wellbeing and, specifically, if it could prove beneficial in regards to memory function.

As with CBD, CBDV also shows potential when it comes to inflammation, and gut inflammation in particular. People suffering from Crohn’s disease and other gastrointestinal conditions take anti-inflammatories that cause serious and unpleasant side effects. A powerful botanical remedy that could diminish gut inflammation would literally change the lives of these patients.

The Significance of Full-Spectrum Hemp Oil

While research is still ongoing regarding CBDV, Synchronicity is developing its own range of products with Full-Spectrum Hemp Oil.

Instead of isolating CBD, our team has dedicated itself to including the whole plant potential in its product range. This means that our Synchronicity Full-Spectrum Oil products contain CBD but also all the other cannabinoids, including CBDV. Even if there are minute quantities of CBDV, they are still interacting with the rest of the cannabinoids to unleash their own power.

Our choice is based on our science-based conviction that when all-natural Hemp compounds work together, they enhance each other’s efficiency. The whole is greater than the sum of all the parts; a theory called in scientific circles the entourage effect.

By giving your body the full benefits of Hemp, you are providing it with all the natural wellness to support your health. When cannabinoids work with terpenes and flavonoids to provide their full potential, your body is benefiting from a sweeping natural wellness boost—what we call the True Entourage Effect™.

Our Full-Spectrum Hemp Oil products are developed with respect to nature and its integrity. Nature has handsomely given us it’s gifts and we honor her by keeping them intact and whole.

Feel the Full Effect™ with Synchronicity and enjoy Hemp the way nature intended.

Synchronicity makes Full-Spectrum Hemp Oil by gently hand-pressing Whole Hemp plants and infusing them into a coconut oil to maintain all the cannabinoid nutrients of the plant. Like CBD, our Hemp Oil comes in many forms, from oils to tinctures to topicals. Unlike CBD, it’s not made by using harsh CO2 extraction processes. So, in the end, you get a cleaner, purer, more potent product. Synchronicity—the Hemp Oil producers you can trust.


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ContentsWhere Does CBDV Come from?Is CBDV Legal in the United States?What Is CBDV’s Potential?CBDV as an AnticonvulsantCBDV as an Anti-EmeticCBDV for Other Health PurposesThe Significance of Full-Spectrum Hemp

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